Research Highlights
See how researchers all across the world are using our software tools to make strides in their research.
Want to be featured on our website and share your work with others?
ProSightPD
-
Proteome Discoverer—A Community Enhanced Data Processing Suite for Protein Informatics
B. C. Orsburn. Proteomes. 2021; 9(1): 15. doi: 10.3390/proteomes9010015
-
Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods.
M. V. D. Waterbeemd et al. Nat Commun. 2018; 9(1):2493. doi: 10.1038/s41467-018-04853-x.
-
Quantitative top down mass spectrometry identifies proteoforms differentially released during mechanical stimulation of mouse skin.
F. Moehring et al. J Proteome Res. 2018; 17(8):2635-2648. doi: 10.1021/acs.jproteome.8b00109. Epub 2018 Jul 6.
-
EThcD and 213 nm UVPD for top-down analysis of bovine seminal plasma proteoforms on electrophoretic and chromatographic time frames. Item
F. P. Gomes et al. Anal Chem. 2020; 92(4):2979-2987. doi: 10.1021/acs.analchem.9b03856. Epub 2020 Jan 29.
-
Protamine characterization by top-down proteomics: Boosting proteoform identification with DBSCAN.
G. Arauz-Garofalo et al. Proteomes. 2021; 9(2):21. doi: 10.3390/proteomes9020021.
TDValidator (now integrated into ProSight Native)
-
Accurate Sequence Analysis of a Monoclonal Antibody by Top-Down and Middle-Down Orbitrap Mass Spectrometry Applying Multiple Ion Activation Techniques
Luca Fornelli, Kristina Srzentić, Romain Huguet, Christopher Mullen, Seema Sharma, Vlad Zabrouskov, Ryan T. Fellers, Kenneth R. Durbin, Philip D.Compton, and Neil L. Kelleher
Anal. Chem., 2018; 90, 14, 8421–8429.
-
Structural Analysis of Monoclonal Antibodies by Ultrahigh Resolution MALDI In-Source Decay FT-ICR Mass Spectrometry
Yuri E.M. van der Burgt, David P. A. Kilgour, Yury O. Tsybin, Kristina Srzentić, Luca Fornelli, Alain Beck, Manfred Wuhrer, and Simone Nicolardi
Anal. Chem., 2019; 91, 3, 2079–2085.
-
Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase
Soo Y. Ro, Luis F. Schachner, Christopher W. Koo, Rahul Purohit, Jonathan P. Remis, Grace E. Kenney, Brandon W. Liauw, Paul M. Thomas, Steven M. Patrie, Neil L. Kelleher, and Amy C. Rosenzweig
Nat Comms., 2019; 10, 2675.